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PRECLINICAL PUBLICATION · 2010

Does inducible NOS have a protective role against hypoxia/reoxygenation injury in rat heart?

Rat / Ischaemia-reperfusion

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 20418118 ↗2010Reported harm

Does inducible NOS have a protective role against hypoxia/reoxygenation injury in rat heart?

RatIschaemia-reperfusionCardiacWistarMalePretreatment10 mg/kgBefore hypoxia

Model: Acute hypobaric hypoxia and reoxygenation of the heart

Inhibiting iNOS with 1400W increased lipid peroxidation and apoptosis, indicating iNOS is protective in the hypoxic heart.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.