THERAPY DOSSIER · th-fef6d0f9ed13

Modified Montoya Staircase reaching and grasping rehabilitation training

Procedure · Rodent forelimb motor-skill assessment and training paradigm; no ChEMBL entity by nature and no human equivalent registered. ClinicalTrials.gov returned no records.

Non-drug Suggest a correction

Evidence & regulatory context

Mechanism: Rodent forelimb motor-skill assessment and training paradigm; no ChEMBL entity by nature and no human equivalent registered. ClinicalTrials.gov returned no records.
Target: Not recorded
Injury models: Spinal cord injury
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 32536855 ↗2020Mixed findings

Reaching and Grasping Training Improves Functional Recovery After Chronic Cervical Spinal Cord Injury.

RatSpinal cord injuryContusionNude ratNot applicable, behavioural trainingTraining 5 days per weekStarted 8 weeks post-injury

Model: Moderate C5 unilateral cervical contusion spinal cord injury, treated at the chronic stage

Rehabilitation increased pellets taken at 13 and 14 weeks post-injury and accuracy from 12 to 14 weeks, and increased serotonergic fibres, presynaptic terminals and reduced GFAP astrogliosis caudal to the lesion, but did not change grooming scores or horizontal ladder misstep rates at any time poin…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

Loading the evidence…