Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Radiation
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 1
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
The Effect of Superoxide Dismutase (SOD) Enzyme on Frailty and Health Related Quality of Life Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial (SOD plus gliadin capsule)
Pre-frail Elderly
Enrolment: 150 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
MouseRadiationWistar albino (as stated by the authors)Femalen = 36 mice randomly distributed into four groupsOral gavage10,000 units per kg per dayTreatment started 6 months after irradiation
Model: Single 25 Gy irradiation, or sham irradiation, producing radiation-induced skin fibrosis assessed 6 months later
Mean dermal thickness was 0.92 plus or minus 0.23 mm in irradiated placebo-treated mice and 0.71 plus or minus 0.17 mm in irradiated superoxide dismutase-gliadin-treated mice, a statistically significant difference (p equals 0.002), with sham-irradiated values of 0.45 plus or minus 0.09 mm (placebo…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.