Subcutaneous Fluids Enabled by Human Recombinant Hyaluronidase (Hylenex) in Healthy Volunteers
Dehydration
Enrolment: 100 · Results not recorded
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Biologic
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Dehydration
Enrolment: 100 · Results not recorded
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Enrolment: 85 · Results not recorded
Multiple Myeloma
Enrolment: 70 · Results not recorded
HIV Infections
Enrolment: 24 · Results not recorded
Healthy Volunteers
Enrolment: 110 · Results not recorded
Healthy
Enrolment: 14 · Results not recorded
Healthy Volunteers
Enrolment: 64 · Results not recorded
Multiple Myeloma
Enrolment: 22 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Retrocalcaneal bursitis and Achilles tendinopathy induced by two injections of recombinant human TGF-beta1 into the retrocalcaneal bursa
rHuPH20 rapidly cleared accumulated hyaluronan and CS/DS, restored geometric and material tendon properties to uninjured levels by 9 days, and produced targeted acute increases in cell fate, extracellular matrix metabolism and inflammatory gene expression. Effects were most evident at the acute and…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.