FEASIBILITY and PRELIMINARY EFFICACY of REPETITIVE TRANS-SPINAL MAGNETIC STIMULATION for GAIT RECOVERY AFTER INCOMPLETE SPINAL CORD INJURY
Spinal Cord Injuries (SCI)
Enrolment: 6 · Results not recorded
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Procedure
2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Spinal Cord Injuries (SCI)
Enrolment: 6 · Results not recorded
Parkinson's Disease (PD) · Gait Disorders · Transcranial Magnetic Stimulation · Spinal Cord Stimulation
Enrolment: 30 · Results not recorded
Adverse Effect of Drug Therapy Levodopa
Enrolment: 38 · Results not recorded
Parkinson Disease · Gait Disorders, Neurologic
Enrolment: 76 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Acute aneurysm-clip compression spinal cord injury: T10 laminectomy, Yasargil titanium mini clip (closing force 70 g) applied at T10 for 10 s
rTSMS at all three segments raised BBB scores versus untreated injury, alleviated myelin damage, lowered Nogo-A, NgR and apoptotic proteins and increased GAP43, with L2 stimulation giving the greatest late motor gain, although the 5-HT immunohistochemistry and immunofluorescence results were intern…
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Model: Laminectomy at T9-T11 with dura removal then complete spinal cord transection with a 25-gauge needle; dorsal funiculus transection sparing the central canal in transgenic mice
rTSMS reduced the fibrotic scar approximately 2-fold at day 15 and 4-fold at day 90, reduced the glial scar core, and reduced Iba1 positive inflammation nearly 3-fold. Demyelinated area fell approximately 4-fold and surviving neurons rose from a mean of 139 to 233 per section, with substantial BDA-…
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