THERAPY DOSSIER · th-f51b74010596

Photobiomodulation with an AlGaAs low-level laser, alone and combined with aquatic exercise (swimming)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 10

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06717633 ↗PHASE3unknown

Comparison of Short-term Effects of Extracorporeal Shock Wave Therapy, Low-level Laser Therapy and Pulsed Electromagnetic Field Therapy in Knee Osteoarthritis

Knee Osteoarthritis

Enrolment: 120 · Results not recorded

NCT01972100 ↗NAcompleted

Use of Low-level Laser Therapy (808nm) to Muscle Fatigue Resistance: a Randomized Double-blind Crossover Trial

Healthy

Enrolment: 7 · Results not recorded

NCT05595564 ↗NAunknown

Influence of Photobiomodulation on Anaerobic Capacity Under Normoxia and Hypoxia Conditions in Treadmill Runners

Low Level Laser Therapy · Photobiomodulation · Performance · Sport

Enrolment: 7 · Results not recorded

NCT07613489 ↗NAactive not recruiting

Effectiveness of Photobiomodulation Therapy in Enhancing Nerve Function and Quality of Life Among Patients With Diabetic Peripheral Neuropathy: A Randomized Controlled Trial

Diabetic Peripheral Neuropathy · Diabetes Mellitus Type 2

Enrolment: 36 · Results not recorded

NCT05279911 ↗NAcompleted

Influence of Low-level Laser Therapy on Radiographic and Biochemical Profiles in Type II Controlled Diabetic Patients After Dental Implant Insertion

Type 2 Diabetes Mellitus · Low-level Laser Therapy · Bone Density Increased

Enrolment: 40 · Results not recorded

NCT07303192 ↗NAcompleted

The Effect of Injectable Platelet-Rich Fibrin and Low-Level Laser Therapy on Graft Shrinkage in Free Gingival Grafts

Graft Shrinkage · Gingival Recession, Localized

Enrolment: 48 · Results not recorded

NCT06520761 ↗NAunknown

The Effect of Injectable Platelet Rich Fibrin Versus Low-Level LASER Therapy on The Rate of Orthodontic Tooth Movement

Rate of Canine Retraction · Root Resorption

Enrolment: 20 · Results not recorded

NCT02891499 ↗NAcompleted

Effect of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants With Mediate and Immediate Force Application

Displacement of Other Bone Devices, Implants and Grafts

Enrolment: 29 · Results not recorded

NCT04897555 ↗NAcompleted

Evaluation of Low Level Light Therapy (LLLT) as a Primary Therapy for Non-Specific Alopecia of the Eyebrow in Women

Alopecia

Enrolment: 40 · Results not recorded

NCT07372443 ↗NAnot yet recruiting

Usefulness of Photobiomodulation in the Prevention and Management of Oral Mucositis in Pediatric Patients Undergoing Antineoplastic Treatment

Oral Mucositis · Chemotherapy Effect · Pediatric Cancer

Enrolment: 49 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 33106989 ↗2020Reported benefit

Effects of photobiomodulation and swimming on gene expression in rats with the tibialis anterior muscle injury.

RatOtherWistarn = n=15 per group across five groups (control, non-treated inj…Transcutaneous laser irradiation over the injured tibialis anterior; swimming for the aquatic exercise arm830 nm wavelength, beam spot 0.0324 cm2, output power 100 m…After cryoinjury

Model: Cryoinjury to the belly of the tibialis anterior muscle

Cryoinjury raised MyoD, myogenin and TGF-beta expression relative to uninjured controls. Photobiomodulation alone further increased expression of all three genes at day 7 with a decline through day 21, whereas aquatic exercise increased expression progressively over time. The combination of photobi…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

Loading the evidence…