Effect of Intraoperative Low Tidal Volume vs Intermediate Tidal Volume on Oxygenation, Respiratory Mechanics, and Pulmonary Complications
Trendelenburg · Neumoperitoneum · Oxygenation · Respiratory · Pulmonary
Enrolment: 130 · Results not recorded
Procedure
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Trendelenburg · Neumoperitoneum · Oxygenation · Respiratory · Pulmonary
Enrolment: 130 · Results not recorded
Low Tidal Volume Ventilation · Acute Respiratory Distress Syndrome
Enrolment: 0 · Results not recorded
Orthopedic Surgery · Ventilation
Enrolment: 2860 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Indirect acute lung injury induced by intravenous lipopolysaccharide (E. coli O111:B4) 6 mg/kg via the femoral vein
Compared with 12 mL/kg, 6 mL/kg ventilation reduced endothelin-1 (113.79 versus 152.52 pg/mL) and TNF-alpha (3305 versus 4144 pg/mL), increased eNOS expression, and improved acetylcholine-induced vasodilatation by about 30%.
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.