Effectiveness of Aqueous Extract of Marine BaitwormIdris, Hutchings and Arshad, 2014 (Annelida, Polychaeta), on Acute Wound Healing Using Sprague Dawley Rats.
RatWoundSprague Dawleymalen = 36 male rats in total across 7 groups, at least 5 animals p…topical application to the wound0.1%, 0.5% and 1.0% (w/w) polychaete extract in emulsifying…Treatment started on the day of wounding (day 0), immediately after wound creat…
Model: Full thickness excisional skin wound created on the dorsum with an 8 mm disposable sterile biopsy punch under diethyl ether anaesthesia
PE 1.0% gave the fastest wound contraction, with wound healing percentage of 35.3% at day 3 (versus 25.2% for gamat oil), 84.6% at day 7, 91.9% at day 11 (versus 85.3% gamat oil and 80.2% untreated) and 98.7% at day 14 (versus 86.8% untreated, 89.5% PE 0.1%, 91.4% PE 0.5%, 90.8% vehicle). Histology…
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.