THERAPY DOSSIER · th-f022e4e4d231

Aloe vera (Aloe barbadensis Miller) 0.5% hydroalcoholic extract

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 3

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT02819817 ↗Injury indicationPHASE1/PHASE2withdrawn

Topical Aloe Vera Gel in ED Patients Presenting With Simple Traumatic Wounds (RCT)

Injuries and Wounds

Enrolment: 0 · Results not recorded

NCT00156806 ↗PHASE3completed

Aloe Barbadensis in Reducing Cutaneous Side-Effects of Radiation Treatment for Breast Cancer

Breast Cancer

Enrolment: 231 · Results not recorded

NCT04942470 ↗NAcompleted

Aloe Vera and Propolis Applied for Pressure Ulcer

Pressure Ulcer

Enrolment: 66 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 25891093 ↗2015No effect reported

Topical Aloe Vera (Aloe barbadensis Miller) Extract Does Not Accelerate the Oral Wound Healing in Rats.

RatWoundWistarmalen = 72 rats, 24 per grouptopical0.5% hydroalcoholic extract, topical applicationafter ulcer creation

Model: Traumatic ulcer of the dorsum of the tongue created with a 3-mm punch tool

No significant difference between Aloe vera, placebo and control groups in repair of oral ulcers at any time point; treatment did not accelerate oral wound healing.

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.

Loading the evidence…