Trial title not recorded
Congenital Hypothyroidism
Enrolment: 101 · Results not recorded
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Hormone · Thyroid hormone receptor agonist
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Congenital Hypothyroidism
Enrolment: 101 · Results not recorded
Euthyroid Sick Syndrome · Cardiac Surgery
Enrolment: 70 · Results not recorded
Non-Alcoholic Fatty Liver Disease · Hepatic Steato-Fibrosis
Enrolment: 60 · Results not recorded
Thyroid Cancer · Papillary Thyroid Carcinoma
Enrolment: 578 · Results not recorded
Primary Hypothyroidism · Aging
Enrolment: 208 · Results not recorded
Recurrent Pregnancy Loss · Euthyroid With Thyroid Antibodies
Enrolment: 796 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Severe traumatic brain injury induced by Feeney free-fall weight-drop method
Thyroxine reduced brain pathology and Neurological Severity Score after injury, most clearly at moderate and high doses, and lowered serum GFAP and S100B. Wnt3a, beta-catenin, Notch1 and Hes1 mRNA and Bcl-2 increased while Bax decreased, and thyroxine had no effect in uninjured rats.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.