The Effect of an Apple Polyphenol Extract Rich in Epicatechin and Flavan-3-ol Oligomers (Evesse EPC) on Brachial Artery Flow-mediated Vasodilatory Function
Borderline Hypertension
Enrolment: 57 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Borderline Hypertension
Enrolment: 57 · Results not recorded
Diabetes · Cardiovascular Diseases · Prediabetes
Enrolment: 50 · Results not recorded
PreDiabetes · Impaired Glucose Tolerance
Enrolment: 8 · Results not recorded
Hyperglycemia, Postprandial · Healthy
Enrolment: 24 · Results not recorded
Healthy
Enrolment: 12 · Results not recorded
Overweight · Obesity
Enrolment: 90 · Results not recorded
Glucose Intolerance
Enrolment: 24 · Results not recorded
Prevention of Hyperglycaemia
Enrolment: 34 · Results not recorded
Healthy
Enrolment: 64 · Results not recorded
Healthy Aging
Enrolment: 30 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Concanavalin A-induced immunological liver injury, single intravenous administration of concanavalin A
Apple polyphenol pretreatment normalised serum transaminases and protein indices, improved liver histopathology, lowered TNF-alpha, IFN-gamma and nitric oxide, and restored MDA, SOD and GSH.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.