Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Insulin Resistance · Mild Cognitive Impairment · Cognitive Decline
Enrolment: 140 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Carbon tetrachloride-induced acute liver injury, 1 ml/kg intraperitoneally (1:3 in corn oil); lethal acute liver failure model at 2.6 ml/kg (1:1 in corn oil)
Oroxylin A lowered serum ALT and AST and necrosis, raised albumin, IL-1Ra and early hepatocyte PCNA positivity, and improved survival after lethal carbon tetrachloride in wild-type mice (p = 0.0033) but not in IL-1RI-/- mice (p = 0.9141).
Extraction: extract · Supplied extraction confidence: 0.92. Machine-extracted fields require source verification.
Model: Lipopolysaccharide induced acute lung injury and endotoxaemia
Post-treatment at 1 h or 6 h reduced lung injury, TNF-alpha, nitric oxide, NF-kappaB activation and HMGB1 release, and improved survival.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
