Amygdalin (Vitamin B17) pretreatment attenuates experimentally induced acute autoimmune hepatitis through reduction of CD4+ cell infiltration.
MouseChemical/toxinmalen = 30 adult male mice, three groupsintraperitoneal5 mg/kgPretreatment before Concanavalin A challenge
Model: Concanavalin A-induced acute autoimmune hepatitis, single intravenous injection of Concanavalin A 15 mg/kg
Amygdalin pretreatment significantly reversed the rises in ALT, AST and MDA, the falls in SOD and GSH, the histological damage and the increased CD4-positive cell infiltration seen after Concanavalin A.
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.