Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
No linked human trial in this dataset.
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Severe acute pancreatitis-associated lung injury
Da-Cheng-Qi decoction reduced pulmonary proinflammatory cytokines and lung pathology in a rat model of severe acute pancreatitis and shortened ARDS duration in patients.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Ileus (intestinal obstruction) rat model, with in vitro assays of somatostatin secretion, IL-6 secretion and wound healing
An eleven-ingredient active compound combination was bioequivalent to Da-Cheng-Qi decoction to some extent across intestinal motility, inflammation and injury readouts and is proposed as a set of quality markers, with PI3K/AKT identified as a probable mediating pathway.
Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.
Model: Severe acute pancreatitis induced by retrograde biliopancreatic duct infusion of 3.5 per cent sodium taurocholate at 0.2 mL/min (1 mL/kg), with secondary acute kidney injury
All doses lowered kidney IL-6 and TNF-alpha and raised IL-4 and IL-10 relative to the model group, with the high dose giving the largest effect and the lowest pancreatic and renal pathological scores. Serum creatinine fell significantly in the high dose group, while blood urea nitrogen did not diff…
Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.
