THERAPY DOSSIER · th-dde68c9b38ed

Cold water immersion (cryotherapy)

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 6

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT02688972 ↗NAcompleted

The Accumulative Effect of Cold Water Immersion in Football Athletes

Athletic Performance

Enrolment: 27 · Results not recorded

NCT02806609 ↗NAcompleted

Cold Water Immersion (10C, 10 min): Muscle Pain, Postural Control and Sleep Quality in Soccer Athletes

Pain · Sleep

Enrolment: 28 · Results not recorded

NCT02497495 ↗NAcompleted

Different Temperatures and Times of Cold Water Immersion in Active Individuals

Cryotherapy Effect

Enrolment: 105 · Results not recorded

NCT04201977 ↗NAcompleted

Comparison of Different Forms of Recovery on Functionality After Physical Exercise (cold water immersion arm)

Cryotherapy Effect · Inflammatory Response

Enrolment: 50 · Results not recorded

NCT03431636 ↗NAunknown

Effect of Different Techniques of Recovery After Fatigue in Para-athletes (immersion vs ice pack)

Pain

Enrolment: 21 · Results not recorded

NCT02902315 ↗NAcompleted

Vitamins C and E Combined With Cryotherapy on Pain, Oxidative Stress and Inflammation After Resistance Exercise

Inflammation · Oxidative Stress · Pain

Enrolment: 26 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 30304134 ↗2018Mixed findings

Cryotherapy: biochemical alterations involved in reduction of damage induced by exhaustive exercise.

MouseOtherSwiss albinoMalen = n = 80 animals randomised into four groups; figure legends…Whole body cold water immersionWhole body immersion with head out at 12 degrees C for 12 m…Immediately after the exhaustion protocol

Model: Exhaustive swimming exercise induced muscle damage; swimming at 31 degrees C carrying a load of 10 per cent of body weight until loss of coordinated movement and failure to surface within 7 s

Cold water immersion after exhaustive exercise reduced reactive species production and inflammatory damage biomarkers and increased cell viability compared with exercise alone, although several between group comparisons were not statistically significant and some conclusions rest on effect size ana…

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.

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