THERAPY DOSSIER · th-dc24b2376169

Low intensity laser irradiation (635 nm or 808 nm diode laser, continuous wave or intensity modulated at 3800 Hz)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 9

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06717633 ↗PHASE3unknown

Shock Wave vs Low-Level Laser vs Pulsed Electromagnetic Field Therapy in Knee Osteoarthritis

Knee Osteoarthritis

Enrolment: 120 · Results not recorded

NCT01972100 ↗NAcompleted

Low-Level Laser Therapy (808 nm) for Muscle Fatigue Resistance

Healthy

Enrolment: 7 · Results not recorded

NCT07613489 ↗NAactive not recruiting

Photobiomodulation Therapy for Nerve Function in Diabetic Peripheral Neuropathy

Diabetic Peripheral Neuropathy

Enrolment: 36 · Results not recorded

NCT05279911 ↗NAcompleted

Low-Level Laser Therapy After Dental Implant Insertion in Type II Diabetic Patients

Type 2 Diabetes Mellitus · Bone Density

Enrolment: 40 · Results not recorded

NCT02891499 ↗NAcompleted

Low-Level Laser Therapy on Stability of Orthodontic Miniscrew Implants

Bone Implant Displacement

Enrolment: 29 · Results not recorded

NCT03803956 ↗NAcompleted

Infrared Low-Level Laser (Photobiomodulation) Before Progressive Running in Soccer Players

Muscle Fatigue · Skeletal Muscle Recovery

Enrolment: 22 · Results not recorded

NCT05759975 ↗NAunknown

Extraoral Photobiomodulation Protocols for Oral Adverse Effects After Haematopoietic Stem Cell Transplantation

Oral Mucositis · Xerostomia

Enrolment: 42 · Results not recorded

NCT02995070 ↗NAunknown

Low Intensity Laser Therapy With Connective Tissue Graft for Root Coverage in Smokers

Gingival Recession

Enrolment: 30 · Results not recorded

NCT01772706 ↗NAcompleted

Low Level Diode Laser (100 mW, 658 nm) for Radiochemotherapy-Induced Mucositis in Head and Neck Cancer

Oral Mucositis · Head and Neck Squamous Cell Carcinoma

Enrolment: 97 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 26225295 ↗2014Mixed findings

Effects of low intensity laser irradiation during healing of infected skin wounds in the rat.

RatWoundTranscutaneous irradiation of the woundRadiant exposures of 1 and 20 J/cm2From day 1 after wounding

Model: Dorsal skin wounds inoculated with bacteria to create infected full-thickness skin wounds, followed to day 19

Irradiation at 635 nm (1 and 20 J/cm2) and intensity modulated 808 nm at 20 J/cm2 gave smaller wound area at day 19 than sham (achieved significance level 0.0105 to 0.0208) with bacterial growth similar to controls, whereas the remaining protocols had no effect on wound area but increased bacterial…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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