THERAPY DOSSIER · th-d668ccff0f44

Thyme (Thymus vulgaris) tincture and syrup, thymol predominant

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 10

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07030855 ↗PHASE4enrolling by invitation

Efficacy of Elixirium Thymi Compositum in the Treatment of Acute Bronchitis in Pediatric Patients (EXOTIC)

Acute Bronchitis

Enrolment: 56 · Results not recorded

NCT05276375 ↗PHASE2completed

Effect of Bronchipret on Antiviral Immune Response in Patients With Mild COVID-19 (BroVID)

COVID-19

Enrolment: 21 · Results not recorded

NCT03331757 ↗NAcompleted

Determination of the Glycemic Index and Glycemic Load of Six Greek Honey Grades

Potential Abnormality of Glucose Tolerance · Appetitive Behavior

Enrolment: 11 · Results not recorded

NCT04880148 ↗NAunknown

Effectiveness of a Thyme and Honey Spray for Oral Mucositis and Xerostomia in Head and Neck Cancer

Cancer of the Head and Neck · Xerostomia · Oral Mucositis

Enrolment: 200 · Results not recorded

NCT06421038 ↗NAunknown

Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers

Aphthous Stomatitis

Enrolment: 20 · Results not recorded

NCT05247008 ↗NAcompleted

Effectiveness of Thyme Honey in Management of Xerostomia in Geriatric Patients With ESRD

Xerostomia

Enrolment: 40 · Results not recorded

NCT07429227 ↗NArecruiting

Metabolomic and Cellular Inflammaging Investigation Study of Patients With Acute Coronary Syndrome

Acute Coronary Syndromes (ACS)

Enrolment: 15 · Results not recorded

NCT01643096 ↗NAunknown

Effect of Thyme and Sumac on the Thermic Effect of Food

Effects of; Food, Allergic

Enrolment: 40 · Results not recorded

NCT01561235 ↗NAcompleted

Contribution of Gastrointestinal Appetite Hormones to Protein-induced Satiety

Obesity

Enrolment: 25 · Results not recorded

NCT06156449 ↗NAunknown

Effect of Thyme Oil on Respiratory Symptoms and Hemodynamic Parameters in COPD Patients

Patient Engagement

Enrolment: 120 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 26683486 ↗2015Mixed findings

Effects of pharmaceutical formulations containing thyme on carbon tetrachloride-induced liver injury in rats.

RatChemical/toxinAlbino WistarMale and femalen = 6 per group across 6 groupsOral gavage, diluted with salineTincture 0.18 ml/kg/day; syrup 5.6 ml/kg/dayPretreatment daily for 7 days before the carbon tetrachloride challenge

Model: Acute liver injury from a single intraperitoneal dose of carbon tetrachloride in olive oil (1:3), 1 ml/kg, given 1 h after the final thyme dose on day 7

Both thyme preparations reduced hepatic lipid peroxidation and normalised antioxidant enzyme activities, but the tincture worsened serum AST and ALT while the syrup lowered them, and neither improved histological liver damage.

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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