Approximate entropy of ACTH and cortisol secretion in patients with head injury (metyrapone)
Brain Injury · Craniocerebral Trauma
Enrolment: 32 · Results not recorded
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Drug · Cytochrome P450 11B1 (11beta-hydroxylase) inhibitor (INHIBITOR; mechanism for indication: Cushing's syndrome)
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Brain Injury · Craniocerebral Trauma
Enrolment: 32 · Results not recorded
Metabolic Syndrome · Obesity · Insulin Resistance
Enrolment: 24 · Results not recorded
Shift Work Schedule · Circadian Rhythm · Insulin Resistance · Circadian Misalignment
Enrolment: 48 · Results not recorded
Autonomous Cortisol Secretion · Mild Autonomous Cortisol Secretion (MACS)
Enrolment: 30 · Results not recorded
Mild Autonomous Cortisol Secretion (MACS) · Autonomous Cortisol Secretion (ACS)
Enrolment: 90 · Results not recorded
Major Depressive Disorder
Enrolment: 63 · Results not recorded
Cocaine Use Disorder · Tobacco Use Disorder
Enrolment: 24 · Results not recorded
Cocaine Use Disorder
Enrolment: 18 · Results not recorded
Cocaine-Related Disorders · Infusions, Intravenous
Enrolment: 12 · Results not recorded
Stress
Enrolment: 256 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Moderate lateral fluid percussion traumatic brain injury at 1.8 to 2.0 atm under isoflurane anaesthesia
Both drugs significantly reduced Fluoro-Jade positive neurons in CA3, without reaching significance in CA1 and CA2, and produced closely similar attenuation of injury-induced cell death, stress and oxidative phosphorylation gene networks.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.