THERAPY DOSSIER · th-d437dc47023c

AlGaInP diode laser at 660 nm and a high frequency generator

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT03000426 ↗Injury indicationNAcompleted

Comparison of Two Energy Densities for Photobiomodulation of Palatal Donor Site After Free Gingival Graft Removal (GaAlAs laser)

Palatal Wound

Enrolment: 45 · Results not recorded

NCT05811195 ↗NAunknown

Comparison of Two Prophylactic Photobiomodulation Protocols in Chemoinduced Oral Mucositis in Paediatric and Adolescent Oncology Patients

Oral Mucositis · Chemotherapeutic Toxicity · Childhood Cancer

Enrolment: 34 · Results not recorded

NCT06217224 ↗NAunknown

Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma Undergoing High Doses of Methotrexate

Mucositis Oral

Enrolment: 53 · Results not recorded

NCT07069153 ↗NAcompleted

Efficacy of Laser Therapy and Ozone Therapy for the Treatment of Oral Mucositis in Cancer Patients

Oral Mucositis · Head and Neck Neoplasms · Hematologic Neoplasms

Enrolment: 40 · Results not recorded

NCT03320460 ↗NAunknown

Efficacy of Photobiomodulation for Oral Lichen Planus Treatment

Lichen Planus, Oral · Low-Level Light Therapy

Enrolment: 44 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 26735049 ↗2015Reported benefit

Action of AlGaInP laser and high frequency generator in cutaneous wound healing. A comparative study.

MouseWoundMalen = 40 mice, 10 per group across four groupsTopical application to the woundLaser 30 mW at 5 J/cm2 or 8 J/cm2 in scan mode for 120 s; h…

Model: Full thickness dorsal excisional wound made with an 8 mm punch

The 660 nm AlGaInP laser at 5 J/cm2 gave the greatest stimulus in the acute phase and 8 J/cm2 in the remodelling phase, while the high frequency generator benefited only the acute phase.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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