Procedure
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Severe Acute Cholangitis
Enrolment: 126 · Results not recorded
Pancreaticoduodenectomy
Enrolment: 322 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Severe acute pancreatitis induced by retrograde injection of 4% sodium taurocholate at 1 mL/kg into the biliopancreatic duct through the duodenal wall
Biliary tract external drainage significantly reduced organ damage and lowered serum amylase, ALT, AST, diamine oxidase, myeloperoxidase and lipopolysaccharide, increased the ability to inhibit hydroxyl radical, reduced tissue tumour necrosis factor alpha and interleukin 6 and increased haem oxygen…
Extraction: extract · Supplied extraction confidence: 0.82. Machine-extracted fields require source verification.
Model: Haemorrhagic shock induced by blood withdrawal from the femoral artery, with acute kidney injury
Biliary tract external drainage markedly increased renal occludin mRNA and protein and significantly reduced renal histopathology scores under haemorrhagic shock. Zinc protoporphyrin IX abolished these effects, implicating the haem oxygenase-1 pathway.
Extraction: extract · Subtype source: review · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.
