Trial title not recorded
Pain
Enrolment: 11 · Results not recorded
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Drug · Cyclooxygenase-2 inhibitor (INHIBITOR; direct interaction, disease efficacy)
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Pain
Enrolment: 11 · Results not recorded
Acute Pain
Enrolment: 45 · Results not recorded
Pain, Postoperative Arthroscopy
Enrolment: 420 · Results not recorded
Cancer of Stomach
Enrolment: 214 · Results not recorded
Prostate Cancer
Enrolment: 15000 · Results not recorded
Pain
Enrolment: 274 · Results not recorded
Postoperative Pain
Enrolment: 450 · Results not recorded
Pain · Tooth Extraction
Enrolment: 136 · Results not recorded
Pain
Enrolment: 150 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: 30 min coronary artery occlusion followed by 120 min reperfusion, with or without ischaemic preconditioning; isolated papillary muscle and adult cardiac myocyte simulated ischaemia/reperfusion
Rofecoxib increased arrhythmias including ventricular fibrillation and prolonged action potential duration during ischaemia/reperfusion, and increased acute mortality, but decreased infarct size and increased survival of cardiac myocytes subjected to simulated ischaemia/reperfusion. The proarrhythm…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.