Pharmacological and chemical study to identify wound-healing active compounds in Ageratina pichinchensis.
MouseWoundBALB/cMale and femaleOralAcute oral 2 g/kg; subchronic oral 1 g/kg for 28 days in th…
Model: Skin wound healing model, with carrageenan-induced inflammation and oral acute and subchronic toxicity testing
Bioguided separation identified 7-O-(beta-D-glucopyranosyl)-galactin as the most active compound for inducing cellular overgrowth, and the aqueous extract reduced carrageenan-induced inflammation by up to 60.6 per cent without affecting hepatic function or liver and kidney histology.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.