Hypersensitivity to Adrenomedullin in Post-Traumatic Headache: A Randomized Clinical Trial
Posttraumatic Headache
Enrolment: 21 · Results not recorded
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Biologic
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Posttraumatic Headache
Enrolment: 21 · Results not recorded
Cadasil
Enrolment: 60 · Results not recorded
Headache, Migraine
Enrolment: 20 · Results not recorded
Acute Myeloid Leukemia
Enrolment: 72 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Permanent middle cerebral artery occlusion focal cerebral ischaemia
Peripheral human adrenomedullin combined with AMBP-1 reduced infarct volume, apoptosis and inflammation after ischaemic stroke in rats, an effect not seen with either agent alone.
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Model: Marmarou diffuse impact-acceleration traumatic brain injury
Plasma interleukin-1beta, interleukin-6 and tumour necrosis factor-alpha and tissue malondialdehyde, myeloperoxidase and glutathione did not differ significantly from the sham group. Neurological scores and histopathological examination nevertheless indicated healing, so the authors conclude that a…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.