THERAPY DOSSIER · th-c7cc4ec85503

Pig skin gel from decellularised gal-gal-knockout porcine skin extracellular matrix with hyaluronic acid, with or without human peripheral blood mononuclear cells

Biologic

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 4

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07632001 ↗Injury indicationNArecruiting

RCT Examining the Effect of Miro3D Wound Matrix on Complete Wound Closure of Chronic Diabetic Foot Ulcers

Diabetic Foot Ulcers · Chronic Wounds

Enrolment: 180 · Results not recorded

NCT01987700 ↗PHASE4completed

RCT Comparing Flex HD Human Acellular Dermal Matrix and Strattice Porcine Acellular Dermal Matrix in Large Abdominal Wall Hernia Repair

Hernia of Abdominal Wall

Enrolment: 120 · Results not recorded

NCT03163654 ↗NAcompleted

Novel Porcine Dermal Matrix Vs Connective Tissue Graft in Multiple Adjacent Gingival Recessions: 12-month RCT

Recession, Gingival

Enrolment: 16 · Results not recorded

NCT02691962 ↗NAcompleted

Post-Market Trial of XenMatrix AB Surgical Graft in Ventral or Incisional Midline Hernias

Incisional Hernia

Enrolment: 75 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 27503828 ↗2016Reported benefit

Significantly Accelerated Wound Healing of Full-Thickness Skin Using a Novel Composite Gel of Porcine Acellular Dermal Matrix and Human Peripheral Blood Cells.

MouseWoundBALB/c nudeFemaleTopical application to the wound

Model: Full-thickness skin excision wound

Wound closure was significantly accelerated by day 15 with the pig skin gel alone or with human peripheral blood mononuclear cells compared with untreated and hyaluronic acid controls, and wounds were completely closed by day 25 with restored bilayer epidermal and dermal structure. Addition of huma…

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.

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