Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
RatChemical/toxinWistarMalen = 35 ratsOral250 and 500 mg/kg body weightPretreatment before induction of myocardial necrosis, with isoprenaline given o…
Model: Isoprenaline-induced myocardial infarction, isoprenaline 85 mg/kg subcutaneously on days 19 and 20 of the pretreatment period
Cardiac enzyme levels altered by isoprenaline were significantly restored by the extract, most clearly at 500 mg/kg (ALT, AST, CK-MB and LDH all p<0.0001), with supporting physical and histopathological findings comparable to the standard drugs.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.