Selenium - ITEDS: A North American Study (sodium selenate in thyroid eye disease)
Thyroid Associated Ophthalmopathies
Enrolment: 0 · Results not recorded
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Drug
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Thyroid Associated Ophthalmopathies
Enrolment: 0 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Lateral fluid percussion injury with sham-injury controls; human post-mortem acute traumatic brain injury brain samples
Injury acutely reduced PR55 expression and protein phosphatase 2A activity and raised phosphorylated tau; 12 weeks of sodium selenate increased protein phosphatase 2A activity and PR55 expression, reduced the phosphorylated to total tau ratio, attenuated brain damage and improved behavioural outcom…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.