THERAPY DOSSIER · th-c1aa592f8a9e

Photobiomodulation therapy at 660 nm

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 3

2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT07699679 ↗Injury indicationNAnot yet recruiting

Impact of Photobiomodulation in Coronary Artery Bypass Surgery (Saphenous Vein Wound Healing)

Coronary Artery Disease · Surgical Wound Healing

Enrolment: 292 · Results not recorded

NCT05072743 ↗Injury indicationNAunknown

Improvement in Sleep and Neurocognitive Function Using Photobiomodulation in Post-Concussion Patients

Post-Concussion Syndrome

Enrolment: 20 · Results not recorded

NCT06703762 ↗NAnot yet recruiting

Efficacy of Photobiomodulation on Wound Healing and IL-6 in Neuropathic Foot Ulcer

Neuropathic Foot Ulcer

Enrolment: 68 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28980210 ↗2017Reported benefit

Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive KChannel/p38-MAPK Signalling Pathway.

MouseChemical/toxinMalePlantar irradiation660 nm, 30 mW, 0.06 cm2 spot, 50 J/cm2

Model: Carrageenan-induced paw oedema, with comparison models of lipopolysaccharide and zymosan-induced inflammation

Photobiomodulation significantly inhibited carrageenan-induced paw oedema but not noxious thermal response, an effect reversed by CB1 or CB2 antagonism and dependent on ATP-dependent potassium channels and p38 MAPK. It reduced IL-6 in paw and spinal cord and restored spinal IL-10, without central c…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

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