Efficacy of a mouthwash containing propolis for the control of plaque and gingivitis versus chlorhexidine-based mouthwash
Gingivitis · Periodontitis · Plaque · Inflammation
Enrolment: 2 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Gingivitis · Periodontitis · Plaque · Inflammation
Enrolment: 2 · Results not recorded
Covid19 · Inflammation
Enrolment: 200 · Results not recorded
Decay, Dental
Enrolment: 80 · Results not recorded
2 studies reported at therapy level; 2 evidence entries itemised.
Model: Gentamicin-induced acute renal toxicity; gentamicin 80 mg/kg body weight administered orally for 7 days
Co-administration of propolis with gentamicin lowered blood urea nitrogen, restored healthy glomeruli with normal cellularity, reduced tubular injury, collagen and reticular fibre deposition, and decreased apoptosis, kidney injury and oxidative stress markers.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Acute nitric oxide synthase inhibition with N-omega-nitro-L-arginine methyl ester (L-NAME) causing oxidative injury in kidney and heart tissue
Propolis significantly changed catalase activity, malondialdehyde and nitric oxide levels in kidney and heart tissue relative to L-NAME alone, consistent with an influence on endothelial nitric oxide production.
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.