Convalescent plasma versus human immunoglobulin for COVID-19 pneumonia
COVID-19 Pneumonia
Enrolment: 196 · Results not recorded
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Biologic
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
COVID-19 Pneumonia
Enrolment: 196 · Results not recorded
Chronic Obstructive Pulmonary Disease
Enrolment: 48 · Results not recorded
Chronic Antibody-mediated Transplant Rejection
Enrolment: 60 · Results not recorded
Steroid-Refractory Pneumonitis
Enrolment: 1 · Results not recorded
Dry Eye
Enrolment: 27 · Results not recorded
Kidney Failure, Chronic
Enrolment: 24 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Cervical clip-compression spinal cord injury: C7-T2 laminectomy then extradural application of a 35 g modified aneurysm clip at C7-T1 for 60 s to produce moderate to severe injury; sham animals received laminectomy without cord compression; all animals received buprenorphine 0.05 mg/kg and 5 mL saline immediately and every 12 h for 3 days
A single 0.4 g/kg intravenous IgG bolus 15 min after cervical clip-compression injury reduced IL-1beta, IL-6 and MCP-1 at 4 h and myeloperoxidase activity, neutrophil counts and matrix metalloproteinase-9 at 24 h, and was associated with less scarring and cavitation, greater tissue preservation, be…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.92. Machine-extracted fields require source verification.