Intrathecal Administration of Expanded Wharton's Jelly MSC in Chronic Traumatic Spinal Cord Injury
Spinal Cord Injury, Chronic
Enrolment: 10 · Results not recorded
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Biologic
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Spinal Cord Injury, Chronic
Enrolment: 10 · Results not recorded
Myocardial Infarction, Acute · Heart Failure
Enrolment: 420 · Results not recorded
Heart Failure
Enrolment: 115 · Results not recorded
Osteoarthritis
Enrolment: 100 · Results not recorded
Amyotrophic Lateral Sclerosis
Enrolment: 20 · Results not recorded
ARDS, Human · Covid-19
Enrolment: 9 · Results not recorded
Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
Enrolment: 9 · Results not recorded
GVHD,Acute · Graft Failure
Enrolment: 12 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Lethal total body ionising irradiation (acute radiation syndrome)
Wharton's jelly mesenchymal stem cells protected mice from a lethal radiation dose even when given up to 24 h after irradiation, and adding tetracycline extended the protective window. Protection was lost when G-CSF or IL-6 were knocked down in the cells or when cells were given to Nrf-2 knockout r…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.