Evidence & regulatory context
- Mechanism
- Not recorded
- Target
- Not recorded
- Injury models
- Wound
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 7
3 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Wound dressing containing silk fibroin with bioactive coating layer vs medicated paraffin gauze for split-thickness skin graft donor sites
Late Complication From Skin Graft · Infection of Skin Donor Site · Impaired Wound Healing · Pain, Intractable
Enrolment: 29 · Results not recorded
Silk fibroin membranes, loaded or not with neurotensin, on open palatal wounds
Wound Healing · Palate; Wound
Enrolment: 66 · Results not recorded
Reconstruction of digital nerve defects using an implanted silk nerve guide (SilkBridge)
Peripheral Nerve Injury Digital Nerve Hand
Enrolment: 4 · Results not recorded
Feasibility of silk fibroin surgical mesh in rotator cuff tear repair enhancement
Rotator Cuff Tear
Enrolment: 20 · Results not recorded
Cross-linked collagen membrane with and without silk fibroin around immediate dental implants
Immediate Implant
Enrolment: 20 · Results not recorded
Silk fibroin-reinforced collagen-based composite membrane for promoting alveolar bone regeneration
Alveolar Bone Loss / Therapy
Enrolment: 80 · Results not recorded
Silk fibroin versus 2-octyl cyanoacrylate mesh: hypersensitivity reactions in shoulder surgery
Hypersensitivity Reactions · Allergic Contact Dermatitis
Enrolment: 350 · Results not recorded
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
Guinea pigWoundAlbinon = 72 guinea pigs in four experimental groups (n = 18 per grou…Onlay myringoplasty (local placement over the perforation)At the time of perforation
Model: Acute perforation of the right tympanic membrane, repaired by onlay myringoplasty
Tympanic membranes treated with silk fibroin or acellular collagen scaffolds closed earlier, showed a trilaminar structure of more uniform thickness, and recovered hearing faster than paper patch or untreated controls.
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.