THERAPY DOSSIER · th-af1197f5d014

Photobiomodulation therapy at 830 nm, compared with topical diclofenac sodium

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Crush
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 1

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06640439 ↗EARLY_PHASE1not yet recruiting

LED Therapy Using 830 Nm in the Mandibular Third Molar Surgery: Double-blind Randomized Clinical Trial

Molar, Third · Photobiomodulation Therapy · Third Molar Surgery

Enrolment: 50 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28983756 ↗2017Reported benefit

Effects of photobiomodulation therapy and topical non-steroidal anti-inflammatory drug on skeletal muscle injury induced by contusion in rats-part 1: morphological and functional aspects.

RatCrushLimb / muscle crushWistarMaleTranscutaneous irradiation over the injured anterior tibialis muscle; topical application for diclofenac830 nm, continuous mode, power output 100 mW, 3.57 W/cm2; 1…1 hour after trauma

Model: Single controlled trauma to the anterior tibialis muscle producing a contusion injury

All photobiomodulation doses improved morphological changes after contusion, with 9 J most effective for fibre and nuclear organisation, while 3 J produced a statistically significant increase in muscle work compared with the injury and diclofenac groups. Topical diclofenac produced only slight mor…

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.

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