Thymoquinone and Metformin in PCOS-Related Disorders
Polycystic Ovary Syndrome
Enrolment: 253 · Results not recorded
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Nutraceutical · Thymoquinone (bioactive constituent of Nigella sativa); no curated ChEMBL mechanism record
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Polycystic Ovary Syndrome
Enrolment: 253 · Results not recorded
Gut Microbiome
Enrolment: 8 · Results not recorded
Immediate Dental Implant Placement
Enrolment: 44 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Sciatic nerve crush injury
No significant differences in axon diameter, myelin thickness or axon density between control, trauma and thymoquinone groups. The authors concluded that thymoquinone has no acute therapeutic effect on acute nerve injury.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Acute toxic shock induced by sub-lethal Samsum ant (Pachycondyla sennaarensis) venom at 600 micrograms/kg intraperitoneally
Venom raised lipid peroxidation in liver and kidney by 848% and 74.5%, halved HDL, doubled cholesterol, raised urea by 70.25% and lowered IFN-gamma and IL-17, whereas thymoquinone lowered lipid peroxidation by 92.82% in liver and 23.59% in kidney, raised glutathione by 13.63% and 18.97%, restored H…
Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.
Model: Morphine-induced kidney injury over 20 consecutive days
Thymoquinone co-administration significantly increased kidney weight and glomerular number and diameter and reduced blood urea nitrogen, serum creatinine and serum nitric oxide compared with morphine alone (P < .05).
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.