THERAPY DOSSIER · th-ab6e56d19b18

Anodal transcranial direct current stimulation (tDCS)

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: TBI
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 8

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT01405378 ↗EARLY_PHASE1completed

Combining tDCS With Robot Therapy for the Impaired Upper Limb in Stroke Rehabilitation

Stroke

Enrolment: 23 · Results not recorded

NCT05726149 ↗NAcompleted

Unihemispheric Concurrent Dual-Site Anodal tDCS Combined With Therapeutic Exercise in Fibromyalgia

Fibromyalgia

Enrolment: 90 · Results not recorded

NCT07014384 ↗NAcompleted

Cerebellar tDCS Effects on Sensorimotor Network in Isolated Cervical Dystonia

Isolated Cervical Dystonia

Enrolment: 15 · Results not recorded

NCT04991428 ↗NAcompleted

Mechanism of Action of tDCS in Neurofibromatosis Type 1

Neurofibromatosis 1

Enrolment: 31 · Results not recorded

NCT04039048 ↗NAunknown

Effects of Cerebellar tDCS During Balance Training on Cerebellar Ataxia

Cerebellar Ataxia

Enrolment: 10 · Results not recorded

NCT04599764 ↗NAcompleted

High Definition tDCS for Early Alzheimer's Disease

Early Alzheimer's Disease

Enrolment: 60 · Results not recorded

NCT02394691 ↗NAcompleted

Daily Left Prefrontal Dorsolateral tDCS on Cognitive Improvement in Disorders of Consciousness

Disorders of Consciousness

Enrolment: 37 · Results not recorded

NCT04341220 ↗NAunknown

Additive Effect of tDCS on Physiotherapeutic Treatment of Children With Balance Deficit

Postural Balance

Enrolment: 26 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 30178319 ↗2018Reported benefit

Increases in Microvascular Perfusion and Tissue Oxygenation via Vasodilatation After Anodal Transcranial Direct Current Stimulation in the Healthy and Traumatized Mouse Brain.

MouseTBIControlled cortical impactn = Four groups of 10 mice each (traumatic brain injury and sha…Transcranial, anode placed around the craniotomy with the counter electrode on the thorax0.1 mA for 15 min per sessionBeginning either 1 week or 3 weeks after traumatic brain injury

Model: Controlled cortical impact using a 3 mm flat-tip impounder at 5 m/s velocity and 2.0 mm depth from the cortical surface

Anodal tDCS increased regional cortical cerebral blood flow bilaterally in both injured and sham animals, dilated arterioles, raised capillary flow velocity and improved tissue oxygenation. Repetitive stimulation improved motor coordination, learning and memory, and spatial working memory. Recovery…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.88. Machine-extracted fields require source verification.

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