THERAPY DOSSIER · th-a858a0ab3f6a

Essential oil of Alpinia zerumbet

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28700006 ↗2017Reported benefit

Effects of the essential oil of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. on healing and tissue repair after partial Achilles tenotomy in rats.

RatOtherWistarMalen = 30 Wistar rats divided into two groups, with each animal se…Topical application to the operated hind pawDiluted to 33 per cent, 0.3 mL/kgFollowing partial Achilles tenotomy

Model: Partial Achilles tenotomy, right hind paw treated and left hind paw used as internal control

Alpinia zerumbet essential oil reduced hyperaemia and inflammatory cell number in the acute phase (p less than 0.001) and, in the sub-acute phase, macrophage counts correlated with fibroblasts (r = 0.17, p = 0.03). At the chronic phase, treated tendons had more fibroblasts and a higher proportion o…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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