THERAPY DOSSIER · th-9d5d5b6d15e0

Surgical rotator cuff repair

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 7

2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT00208338 ↗Injury indicationPHASE4completed

Randomised pilot study of full thickness rotator cuff tear repair with or without porcine small intestine submucosa (RESTORE)

Arm Injuries

Enrolment: 33 · Results not recorded

NCT03084068 ↗Injury indicationNAcompleted

Efficacy of supraspinatus tendon repair using a human dehydrated umbilical cord patch

Supraspinatus Tear · Shoulder Injury

Enrolment: 25 · Results not recorded

NCT01498198 ↗NAunknown

Non-operative management versus expedited surgery in workers compensation patients with small rotator cuff tears

Rotator Cuff Tear

Enrolment: 144 · Results not recorded

NCT05925881 ↗NArecruiting

Arthroscopic assisted lower trapezius tendon transfer versus bridging repair for irreparable rotator cuff tears

Rotator Cuff Tears

Enrolment: 60 · Results not recorded

NCT02631486 ↗NAcompleted

Does early mobilisation after surgical repair of rotator cuff tears improve biomechanical and clinical outcomes?

Shoulder · Rehabilitation

Enrolment: 20 · Results not recorded

NCT03533088 ↗NAcompleted

Comparing two rehabilitation protocols in patients with rotator cuff repair

Rotator Cuff Tear

Enrolment: 54 · Results not recorded

NCT00253864 ↗NAcompleted

Functional outcome following shoulder surgery: single row versus double row repair, prospective database

Rotator Cuff Tear

Enrolment: 90 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29929403 ↗2018Mixed findings

Biomechanical properties of the repaired and non-repaired rat supraspinatus tendon in the acute postoperative period.

RatOtherSprague-DawleyFemalen = 48 ratsSurgicalAt the time of surgical detachment

Model: Surgical detachment of the supraspinatus (rotator cuff) tendon

Both repaired and unrepaired tendons had significantly inferior mechanical properties compared with healthy controls at both 12 and 19 days. Repaired tendons showed significant increases in peak, equilibrium and ultimate stress, modulus and stiffness and significant decreases in cross-sectional are…

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

Loading the evidence…