Mesenchymal stem cells (bone marrow derived or aortic vascular wall resident); comparator SOD mimetic EUK134

Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression

Model: Whole thorax irradiation mouse model of radiation-induced pneumopathy

Adoptive transfer of bone marrow or vascular wall derived MSCs shortly after whole thorax irradiation limited endothelial cell loss and fibrosis progression and restored SOD1 levels.

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Activation of interleukin‐6–induced glycoprotein 130/signal transducer and activator of transcription 3 pathway in mesenchymal stem cells enhances hepatic differentiation, proliferation, and liver regeneration

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The radiation protection and therapy effects of mesenchymal stem cells in mice with acute radiation injury

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HPMA-RGD hydrogels seeded with mesenchymal stem cells improve functional outcome in chronic spinal cord injury

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Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis

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Electro-acupuncture promotes differentiation of mesenchymal stem cells, regeneration of nerve fibers and partial functional recovery after spinal cord injury

Model: Transected (acute) spinal cord injury

Electro-acupuncture plus MSC transplantation enhanced MSC differentiation, nerve fiber regeneration and partial locomotor recovery after SCI.

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BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury

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Glial cell line-derived neurotrophic growth factor increases motility and survival of cultured mesenchymal stem cells and ameliorates acute kidney injury

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Functional recovery in acute traumatic spinal cord injury after transplantation of human umbilical cord mesenchymal stem cells

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Intravenous administration of mesenchymal stem cells derived from bone marrow after contusive spinal cord injury improves functional outcome

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Modulation of cytokine and nitric oxide by mesenchymal stem cell transfer in lung injury/fibrosis

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Therapeutic effects of human mesenchymal stem cells on traumatic brain injury in rats: secretion of neurotrophic factors and inhibition of apoptosis

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Autologous bone marrow-derived cultured mesenchymal stem cells delivered in a fibrin spray accelerate healing in murine and human cutaneous wounds

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Transplanted mesenchymal stem cells are effective for skin regeneration in acute cutaneous wounds

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Effect of neural-induced mesenchymal stem cells and platelet-rich plasma on facial nerve regeneration in an acute nerve injury model

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