THERAPY DOSSIER · th-99cd6c0eabdf

Therapeutic low-level laser photobiomodulation at 405 nm, 532 nm, 660 nm and 810 nm

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Burn
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 10

4 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT06185426 ↗Injury indicationEARLY_PHASE1unknown

Histopathological, Biochemical And Electrophysiological Evaluation Of Single Or Combined Use Of Diode Laser/Steroid Treatment On Facial Nerve Injury

Nerve Injury · Facial Nerve Injuries

Enrolment: 35 · Results not recorded

NCT03031223 ↗Injury indicationNAunknown

Evaluation of Sensory-motor Response to Low-level Laser Therapy for the Treatment of Spinal Injuries - Protocol for a Randomized, Controlled, Clinical Trial

Spinal Cord Injuries

Enrolment: 30 · Results not recorded

NCT07453927 ↗Injury indicationNArecruiting

Blue Light in the Treatment of Donor Site in Burn Patient: a Controlled Clinical Trial

Donor Site Complication · Burn

Enrolment: 25 · Results not recorded

NCT07699679 ↗Injury indicationNAnot yet recruiting

Impact of Photobiomodulation in Coronary Artery Bypass Surgery: Saphenous Vein Harvesting Techniques, Functional Capacity and Wound Healing

Coronary Artery Disease · Surgical Wound Healing

Enrolment: 292 · Results not recorded

NCT06761950 ↗NAcompleted

Early Photobiomodulation Therapy on Pain and Range of Motion Following Flexor Tendon Repair

Flexor Tendon Rupture · Flexor Tendon Repair

Enrolment: 44 · Results not recorded

NCT07123285 ↗NAnot yet recruiting

Effect of Photobiomodulation on the Healing of Lower-Limb Venous Ulcers: A Randomized, Double-Blind, Controlled Clinical Trial

Venous Leg Ulcer · Chronic Venous Insufficiency

Enrolment: 102 · Results not recorded

NCT04689009 ↗NAcompleted

Multi-centre, Randomized Controlled, Prospective Study on Speed of Healing, Quality of Life and Cost-effectiveness of the Blue Light Medical Device EmoLED vs Standard Treatment for Leg Ulcers (L.U.C.E. Study)

Venous Leg Ulcer · Mixed Leg Ulcer

Enrolment: 83 · Results not recorded

NCT00860717 ↗NAcompleted

Clinic-Epidemiological Evaluation of Ulcers in Leprosy Patients and the Use of Low Level Laser Therapy: a Randomized Clinical Trial

Leprosy

Enrolment: 25 · Results not recorded

NCT06248541 ↗NAunknown

The Effect of Low-Level Laser Therapy in Carpal Tunnel Syndrome: A Randomized, Single-Blinded, Placebo-Controlled Trial

Carpal Tunnel Syndrome

Enrolment: 40 · Results not recorded

NCT04949373 ↗NAcompleted

Evaluation of the Efficacy of High Intensity Laser (HILT) Therapy in Idiopathic Carpal Tunnel Syndrome

Carpal Tunnel Syndrome · Entrapment Neuropathy

Enrolment: 60 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28166437 ↗2017No effect reported

Evaluation of therapeutic laser influences on the healing of third-degree burns in rats according to different wavelengths

RatBurnUnspecifiedWistarMalen = 60 male Wistar rats allocated across five groupsTranscutaneous laser irradiation of the burn wound1.5 J/cm2 energy density at 200 mW/cm2 power density

Model: Third-degree dorsal skin burn created with a 95 degrees C copper stamp under anaesthesia

All laser groups showed greater reduction in wound size than the untreated control, but differences were not statistically significant except between the red and blue laser groups on the final day. The authors concluded that green, blue, red and infrared wavelengths may accelerate healing, with the…

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

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