THERAPY DOSSIER · th-97a25cc2d896

Dietary restriction by alternate-day fasting

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Ischaemia-reperfusion
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 5

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT04732130 ↗NAcompleted

Longitudinal monitoring during different intermittent fasting protocols including alternate day fasting in non-obese adults

Intermittent Fasting · Overweight · Time Restricted Feeding

Enrolment: 76 · Results not recorded

NCT06963437 ↗NAcompleted

Revisional surgery, ketogenic diet and intermittent fasting in bariatric surgery patients with weight regain

Weight Regain Post Bariatric Surgery · Intermittent Fasting

Enrolment: 43 · Results not recorded

NCT03696966 ↗NAcompleted

KU alternate meal energy level study (intermittent very-low calorie diet)

Obesity · Weight Loss

Enrolment: 35 · Results not recorded

NCT05420311 ↗NAunknown

Personalised medicine in the dietary approach to obesity, intermittent fasting arm

Obesity

Enrolment: 450 · Results not recorded

NCT04259632 ↗NAcompleted

Prolonged daily fasting as a viable alternative to caloric restriction in at-risk obese humans

Obesity

Enrolment: 115 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 22217415 ↗2012Reported benefit

Impact of aging and diet restriction on retinal function during and after acute intraocular pressure injury.

MouseIschaemia-reperfusionOther / unspecifiedC57BL/6JFemaleDietaryAlternate-day fastingCommenced at 12 months of age and maintained for 6 months before the intraocula…

Model: Acute subischaemic retinal injury induced by intraocular pressure elevation, used as an optic nerve stress test

Older 18-month-old mice lost more inner retinal function after intraocular pressure challenge than younger adults. Dietary restriction improved recovery of inner retinal function after the challenge relative to ad libitum fed age-matched controls, and was associated with lower post-injury oxidative…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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