IK-1001 (Sodium Sulfide, H2S donor) in Acute STEMI Undergoing Primary PCI
ST-Segment Elevation Myocardial Infarction
Enrolment: 0 · Results not recorded
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Drug · H2S gasotransmitter; not a discrete ChEMBL drug (nearest H2S-donor entry SODIUM SULFIDE, CHEMBL2107611)
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
ST-Segment Elevation Myocardial Infarction
Enrolment: 0 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Middle cerebral artery occlusion (MCAO) model of focal cerebral ischaemia; in vitro oxygen-glucose deprivation in cultured astrocytes and endothelial cells
Hydrogen sulfide augmented angiogenesis in the peri-infarct area and significantly improved functional outcome at 2 weeks in the rat MCAO model. Treated rats showed 2.31-fold more newly synthesised endothelial cells in the ischaemic lesion (p<0.01). In vitro, hydrogen sulfide increased endothelial…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.