Preliminary Characterization, Antioxidant and Hepatoprotective Activities of Polysaccharides from Taishan Pinus massoniana Pollen.
RatChemical/toxinWistarMalen = 36 rats in the hepatoprotection study, six groups of sixIntragastric100, 200 and 400 mg/kg body weight in 2.0 mL; positive cont…Pretreatment for 14 consecutive days before CCl4 challenge on day 15
Model: Carbon tetrachloride-induced acute hepatic injury; single 50% CCl4 in peanut oil, 2.0 mL/kg body weight, intraperitoneal, on day 15
Pretreatment at 200 and 400 mg/kg dose-dependently reduced serum transaminases, ALP, LDH and hepatic MDA, raised SOD and GSH-Px and lessened histological damage.
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