Inhaled Human Alpha-1 Antitrypsin in Alpha-1 Antitrypsin Deficient Patients With Emphysema
Emphysema
Enrolment: 168 · Results not recorded
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Biologic · Leukocyte elastase inhibitor (INHIBITOR); replacement enzyme
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Emphysema
Enrolment: 168 · Results not recorded
Eosinophilic Esophagitis
Enrolment: 15 · Results not recorded
Type 1 Diabetes Mellitus
Enrolment: 5 · Results not recorded
ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease
Enrolment: 32 · Results not recorded
Alpha1-Antitrypsin Deficiency
Enrolment: 4 · Results not recorded
Chronic Pancreatitis
Enrolment: 48 · Results not recorded
Coronavirus
Enrolment: 150 · Results not recorded
Alpha-1 Antitrypsin Deficiency
Enrolment: 120 · Results not recorded
Alpha1-Antitrypsin Deficiency
Enrolment: 500 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Ventilator-induced lung injury from mechanical ventilation; ventilation parameters and duration not stated in the retrieved text
Mechanical ventilation caused histological lung injury with altered PaO2/FiO2 ratio, wet-to-dry weight ratio and bronchoalveolar lavage protein. Intravenous alpha 1-antitrypsin improved these parameters and reduced inflammation, with fewer BALF neutrophils, lower BALF cytokines and serum adhesion f…
Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.