Effects of 8-week Hydrogen-rich Water Consumption on Body Composition, Appetite and Obesity-specific Quality of Life
Obesity
Enrolment: 36 · Results not recorded
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Other · Hydrogen-saturated drinking water; not a ChEMBL drug entity. One relevant human trial of hydrogen-rich water identified (obesity indication); no trauma-indication trial found. Four further hits (gargling agents, EV71 vaccine, simethicone, lactulose hydrogen breath test, deuterium oxide tracer) were term collisions and were rejected.
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Obesity
Enrolment: 36 · Results not recorded
1 studies reported at therapy level; 1 evidence entries itemised.
Model: Controlled cortical impact to the right parietotemporal cortex via 4 mm craniotomy, 3 mm flat tip at 5.82 m/s to a depth of 1.2 mm for 47 ms at 73 psi driving pressure; sham mice underwent the full procedure without impact
Molecular hydrogen water roughly halved controlled cortical impact induced brain edema at 24 h and reversed the Keep edema index, abolished AT8 and Alz50 pathological tau staining in cortex and hippocampus, reduced Iba1 microglial activation and GFAP staining, restored AQP-4 and MMP-2, partly suppr…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.95. Machine-extracted fields require source verification.