THERAPY DOSSIER · th-8f6c0cc2ede1

human glial precursor-derived astrocytes (BMP-induced, GDA-BMP)

Biologic

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Spinal cord injury
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 21407803 ↗2011Reported benefit

Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury.

RatSpinal cord injuryComplete transectionFemaletransplantation into injury siteacute

Model: acute transection spinal cord injury

BMP-derived human astrocytes promoted behavioural recovery, neuronal survival and axon growth, unlike CNTF-derived astrocytes.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

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