Validity and Security of Reh-acteoside Therapy for Patients of IgA Nephropathy
IGA Nephropathy
Enrolment: 75 · Results not recorded
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Nutraceutical
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
IGA Nephropathy
Enrolment: 75 · Results not recorded
Cognition Disorders in Old Age
Enrolment: 99 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: D-galactosamine and lipopolysaccharide (GalN/LPS) induced acute hepatic injury in mice; acteoside metabolites first profiled and isolated from rat urine after acteoside administration
Acteoside metabolites showed higher hepatoprotective activity than native acteoside; hydroxytyrosol treatment reduced TNF-alpha to 280 +/- 14.3 ng/L compared with 429 +/- 9.20 ng/L in the model group (p<0.01).
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.
Model: Incision and excision wound models; carrageenan-induced paw oedema
Verbascum mucronatum extract and isolated verbascoside showed significant wound healing, anti-inflammatory and antinociceptive activity.
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Contusive spinal cord injury; laminectomy at T11 with a 13.5 g rod of 1 mm tip diameter dropped from 3 cm onto the exposed L1 segment, approximately 13.5 kdyn, treated in the chronic phase
Intramuscular acteoside in chronic spinal cord injured mice significantly improved Basso Mouse Scale and Toyama Mouse Score, increased gastrocnemius and tibialis anterior weights and increased caudal 5-HT axonal and presynaptic density relative to vehicle.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.