Methionine dietary supplementation potentiates ionizing radiation-induced gastrointestinal syndrome.
MouseRadiationCBA/CaJMaleDietaryMethionine-supplemented diet containing 19.5 mg/kg versus 6…
Model: Caesium-137 total body irradiation at 3 to 8.5 Gy, and partial body irradiation with hindlimb shielding, producing gastrointestinal acute radiation syndrome
Mice on the methionine-supplemented diet developed acute radiation toxicity at doses as low as 3 Gy and showed 50 per cent mortality after 8.5 Gy partial body irradiation, together with gut dysbiosis, leaky gut and bacterial translocation, lower circulating citrulline and reduced mucosal surface ar…
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