THERAPY DOSSIER · th-88a99d90322f

Manual therapy applied to the ankle and knee of the injured limb, with analgesic comparators including morphine, ketorolac and prednisone

Procedure

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 4

1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT04902274 ↗Injury indicationNAterminated

Effectiveness of Transcranial Direct Current Stimulation in Musculoskeletal Rehabilitation (physical therapy comparator)

Ankle Sprains · Musculoskeletal Injury

Enrolment: 41 · Results not recorded

NCT02252276 ↗NAcompleted

Effects of Manual Therapy and Exercise in the Treatment of Recurrent Ankle Sprains: Randomised Trial

Ankle Sprains

Enrolment: 54 · Results not recorded

NCT02025569 ↗NAterminated

The Effectiveness of Strain Counterstrain in the Treatment of Patients With Chronic Ankle Instability

Other Instability, Ankle and Foot

Enrolment: 27 · Results not recorded

NCT05459623 ↗NAcompleted

Effects of Myofascial Release With and Without EMMETT Technique in Iliotibial Band Syndrome

Iliotibial Band Syndrome

Enrolment: 22 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24084801 ↗2013No effect reported

Influence of manual therapy on functional mobility after joint injury in a rat model.

RatOtherMaleManual therapy applied externally to the ankle and knee; analgesics administered separatelyAfter induction of carrageenan joint injury

Model: Acute inflammatory joint injury induced by intra-articular injection of carrageenan into the ankle

Carrageenan injection increased ankle diameter by 64 per cent and reduced running distance by 91 per cent, but neither manual therapy nor analgesic medications restored running wheel activity relative to untreated injured rats.

Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

Loading the evidence…