THERAPY DOSSIER · th-87a8d0ebac38

Low-level laser therapy at 904 nm, compared with topical sodium diclofenac and cryotherapy

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Crush
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 4

2 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT05989815 ↗Injury indicationNAcompleted

Effect of whole-body photobiomodulation on muscular performance enhancement

Muscle Damage · Musculoskeletal Pain · Injury Prevention

Enrolment: 30 · Results not recorded

NCT03751306 ↗Injury indicationNAunknown

Sensory-motor and cardiorespiratory rehabilitation with transcranial laser therapy in central nervous system injury

Spinal Injuries · Post-Traumatic Headache · Post Stroke

Enrolment: 90 · Results not recorded

NCT04725513 ↗NAcompleted

Shockwave therapy, combined shockwave plus photobiomodulation, and physical therapy in non-insertional Achilles tendinopathy

Achilles Tendinopathy

Enrolment: 46 · Results not recorded

NCT06692998 ↗NAnot yet recruiting

Comparison of high and low level laser therapy in De Quervain's tenosynovitis

De Quervain Tendinopathy

Enrolment: 40 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 23812849 ↗2014Mixed findings

What is the best treatment to decrease pro-inflammatory cytokine release in acute skeletal muscle injury induced by trauma in rats: low-level laser therapy, diclofenac, or cryotherapy?

RatCrushLimb / muscle crushWistarMaleTranscutaneous laser irradiation; topical diclofenac; topical cryotherapy904 nm, superpulsed, 700 Hz, 60 mW mean output power, 1.67…1 hour after trauma

Model: Single controlled trauma to the tibialis anterior muscle

Low-level laser therapy at the 1 J dose significantly decreased IL-1 beta, IL-6 and TNF-alpha compared with the non-treated injured group and with the diclofenac and cryotherapy groups. Diclofenac and cryotherapy did not reduce pro-inflammatory cytokine levels relative to the non-treated injured gr…

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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