THERAPY DOSSIER · th-83ff8e37f91d

Vascular endothelial growth factor combined with platelet-derived growth factor

Biologic

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Spinal cord injury
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 24836764 ↗2014Reported benefit

An acute growth factor treatment that preserves function after spinal cord contusion injury.

RatSpinal cord injuryContusionWistarfemaleOsmotic minipump delivery to the injury siteDelivery began immediately after injury

Model: Contusion spinal cord injury

Combined growth factor treatment gave BBB scores of about 18 compared with about 10 in controls, with reduced lesion cavity size and reduced glial activation.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.

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