THERAPY DOSSIER · th-7fdd234f7eb0

Cooked navy bean or black bean dietary supplementation

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Chemical/toxin
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 6

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

NCT02342340 ↗NAcompleted

Blinded, Randomized, Controlled Study to Examine the Bioavailability of Compounds From Different Bean Varieties in Healthy Individuals

Healthy

Enrolment: 8 · Results not recorded

NCT01911390 ↗NAcompleted

Effect of Rice Bran and Cooked Navy Beans on Cholesterol Levels in Healthy Children (Healthy Hearts Program)

Hyperlipidemias

Enrolment: 41 · Results not recorded

NCT04396275 ↗NAcompleted

The Effect of Cooked Whole Navy Beans and Yellow Peas on Short-term Satiety and Food Intake in Children

Satiety · Eating

Enrolment: 53 · Results not recorded

NCT05182190 ↗NAcompleted

Effects of Black Bean Pasta Consumption on Biomarkers in Young Adults

Glucose, High Blood

Enrolment: 18 · Results not recorded

NCT05818358 ↗NAcompleted

Pilot Study of Beans and Whole Grains at Breakfast on Postprandial Vascular Responses in People With Arterial Stiffness

Arterial Stiffness

Enrolment: 11 · Results not recorded

NCT01190384 ↗NAcompleted

Bean Consumption: A Pilot Study in Overweight Men and Women on Immuno-metabolic and Food Intake Endpoints

Metabolic Syndrome

Enrolment: 12 · Results not recorded

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29631142 ↗2018Reported benefit

Navy and black bean supplementation attenuates colitis-associated inflammation and colonic epithelial damage.

MouseChemical/toxinC57Bl/6MaleOral, dietaryIsocaloric 20% cooked navy bean or black bean dietPrefeeding for 3 weeks before colitis induction, switched to control basal diet…

Model: Acute colitis induced by dextran sodium sulfate, 2% w/v in drinking water for 5 days followed by 3 days of fresh water

Bean prefeeding attenuated the acute colitis phenotype, lowering colonic and serum inflammatory mediators and inflammatory transcription factor activation, while raising wound repair markers and epithelial barrier gene expression versus basal diet (P<=0.05).

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

Loading the evidence…